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Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels throughout sleep. Low oxygen levels throughout sleep are a clinical indicator of the severity of sleep apnea, a disorder that will increase the danger of heart illness, dementia, and loss of life. The research, printed at this time in the American Journal of Human Genetics, was funded by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health. "A person’s common blood oxygen levels throughout sleep are hereditary, and comparatively simple to measure," stated study author Susan Redline, M.D., senior physician within the Division of Sleep and Circadian Disorders at Brigham and Women’s Hospital, and professor at Harvard Medical School, Boston. After we sleep, the oxygen level in our blood drops, due to interruptions in respiration. Lung and sleep disorders are likely to decrease these levels additional, and dangerously so. But the vary of these ranges throughout sleep varies broadly between people and, researchers suspect, is greatly influenced by genetics.
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