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Objective: The target of this examine was to determine the effect of thoracic spine mobilization on coronary heart rate,respiratory charge, blood stress and blood oxygen saturation. Study Design: It was a quasi experiment examine. Place and Duration of Study: The examine was carried out in the division of Physical Therapy and Rehabilitation Center,Pakistan Railway Hospital Rawalpindi. Materials and Methods: Ninety six healthy grownup people were selected for the study by convenient sampling method. The inclusive standards of wholesome individuals aged 20-60 years with regular vitals; Blood Pressure: 90/60 mmHg Diastolic, 140/100 mmHg Systolic, Breathing: 12-25 breaths per minute, Pulse: 60 -120 beats per minute and Temperature: 98.6 levels Fahrenheit.Subjects with spinal injury or deformity were not included in the examine. 4.7, male to feminine ratio was 1:1. Majority of the studyr participants (45%) had normal BMI. Thoracic spine mobilization brought about vital change in oxygen saturation.The heart Rate (HR), Respiratory Rate (RR), both systolic and diastolic blood strain (BP) had no significant affiliation with the age, gender or the BMI of research contributors. However blood oxygen saturation confirmed a statistically important association with above mentioned variables. Conclusion: It is concluded that mobilization on thoracic spine (T1-T4) causes a sudden elevation in coronary heart rate, respiratory rate, blood pressure and no main change in blood oxygen saturation.

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