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Quantitatively determining physiological parameters at a microscopic degree within the retina furthers the understanding of the molecular pathways of blinding diseases, equivalent to diabetic retinopathy and glaucoma. A necessary parameter, which has yet to be quantified noninvasively, is the retinal oxygen metabolic fee (rMRO 2). Quantifying rMRO 2 is challenging as a result of two parameters, the blood stream charge and hemoglobin oxygen saturation (sO 2), should be measured collectively. We mixed photoacoustic ophthalmoscopy (PAOM) with spectral area-optical coherence tomography (SD-OCT) to tackle this challenge, in which PAOM measured the sO 2 and SD-OCT mapped the blood stream price. This quantitative methodology might shed new mild on both fundamental analysis and clinical care in ophthalmology in the future. T he demand for treating blindness and low imaginative and prescient continue to escalate as human longevity will increase worldwide. By 2004 1 , for instance, blindness and low vision had affected more than three million Americans aged 40 years and older; by 2010 2 , 285 million individuals globally were affected.
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